Publications
Peer-reviewed articles in journals
J. Štšepetova, M. Rätsep, O. Gerulis, A. Jõesaar, M. Mikelsaar, E. Songisepp. Impact of Lactiplantibacillus plantarum Inducia on metabolic and antioxidative response in cholesterol and BMI variable indices: randomised, double-blind, placebo-controlled trials. Beneficial Microbes: 0 (0)- Pages: 1 - 16. https://doi.org/10.3920/BM2022.0030
Agne Vasiliauskaite, Justina Mileriene, Epp Songisepp, Ida Rud, Sandra Muizniece-Brasava, Inga Ciprovica, Lars Axelsson, Liis Lutter, Elvidas Aleksandrovas, Ene Tammsaar, Joana Salomskiene, Loreta Serniene, Mindaugas Malakauskas. Application of Edible Coating Based on Liquid Acid Whey Protein Concentrate with Indigenous Lactobacillus helveticus for Acid-Curd Cheese Quality Improvement. Foods 2022, 11(21), 3353; https://doi.org/10.3390/foods11213353
Merle Rätsep, Liina Kuus, Kalle Kilk, Merle Muruvee, Sirje Kuusik, Oksana Gerulis, Mirjam Vallas, Epp Songisepp. Variety of Functional Characteristics of the Probiotic Lactobacillus Plantarum Inducia Contribute to the Prevention of Clostridioides Difficile Spore Germination. Scientific Literature Gastroenterology. https://www.scientificliterature.org/Gastroenterology/Gastroenterology-22-132.pdf
Epp Songisepp, Jelena Štšepetova, Merle Rätsep, Liina Kuus, Anneli Piir, Kalle Kilk, Marika Mikelsaar. Polyfunctional metabolic properties of the human strain Lactiplantibacillus plantarum Inducia (DSM 21379): Experimental and clinical approaches. Volume 92, May 2022, 105064. https://doi.org/10.1016/j.jff.2022.105064
Epp Sepp, Imbi Smidt, Tiiu Rööp, Jelena Štšepetova, Siiri Kõljalg, Marika Mikelsaar, Indrek Soidla, Mare Ainsaar, Helgi Kolk, Mirjam Vallas, Madis Jaagura and Reet Mändar. Comparative Analysis of Gut Microbiota in Centenarians and Young People: Impact of Eating Habits and Childhood Living Environment. Front. Cell. Infect. Microbiol., 15 March 2022 Sec. Microbiome in Health and Disease. https://doi.org/10.3389/fcimb.2022.851404
Marika Mikelsaar, Jelena Štšepetova, Raik-Hiio Mikelsaar, Kai Truusalu, Imbi Smidt, Pirje Hütt, Merle Rätsep, Epp Songisepp. Polyamines of human strain Lactobacillus plantarum Inducia induce modulation of innate immune markers. Journal of Functional Foods, Volume 72, September 2020, 104064. https://doi.org/10.1016/j.jff.2020.104064
Epp Sepp, Imbi Smidt, Jelena Štšepetova, Tiiu Rööp, Pirje Hütt, Merle Rätsep, Marika Mikelsaar (2018) The effect of Lactobacillus fermentum ME-3 on the intestinal microbiota and urine polyamines content: A double-blind placebo-controlled pilot trial. Journal of Functional Foods Volume 48, September 2018, Pages 430-438
Henno, Merike; Ariko, Tiia; Kaart, Tanel; Kuusik, Sirje; Ling, Katri; Kass, Marko; Jaakson, Hanno; Leming, Ragnar; Givens, D.Ian; Sterna, Vita; Ots, Meelis (2018). The Fatty acid composition of Estonian and Latvian retail milk; implications for human nutrition compared with a designer milk. Journal of Dairy Research , 85 (2), 247−250.
Ausmees K., Ehrlich-Peets K., Vallas M., Veskioja A., Rammul K., Rehema A., Zilmer M., Songisepp E., Kullisaar T. (2018) Fermented whey product improves the quality of life of males with moderate urinary tract symptoms. PlosOne accepted
Ling, Katri; Henno, Merike; Jõudu, Ivi; Püssa, Tõnu; Jaakson, Hanno; Kass, Marko; Anton, Dea; Ots, Meelis (2017). Selenium supplementation of diets of dairy cows to produce Se-enriched cheese. International Dairy Journal, 71, 76−81.
Jõudu, I., Henno, M., Kaart, T., Veskioja, A., & Ots, M. (2017). Changes in rheological properties of Edam-type cheese during ripening. Agricultural and Food Science, 26(4), 198–206. https://doi.org/10.23986/afsci.63132
Rätsep M., Kõljalg S., Sepp E., Smidt I., Truusalu K., Songisepp E., Stsepetova J., Naaber P., Mikelsaar R.H., Mikelsaar M. (2017). A combination of the probiotic and prebiotic product can prevent the germination of Clostridium difficile spores and infection. Anaerobe. Oct, 47:94-103.
Mikelsaar M., Sepp E., Štšepetova J., Songisepp E., Mändar R. (2016). Biodiversity of Intestinal Lactic Acid Bacteria in the Healthy Population. Adv Exp Med Biol. 932:1-64
Ariko, Tiia; Kass, Marko; Henno, Merike; Fievez, Veerle; Kärt, Olav; Kaart, Tanel; Ots, Meelis (2015). The effect of replacing barley with glycerol in the diet of dairy cows on rumen parameters and milk fatty acid profile. Animal Feed Science and Technology, 209, 69−78.
Le Roy CI., Štšepetova J., Sepp E., Songisepp E., Claus SP., Mikelsaar M. (2015). New insights into the impact of Lactobacillus population on host-bacteria metabolic interplay. Oncotarget. Oct 13,6(31): 30545-56.
Hütt P., Songisepp E., Rätsep M., Mahlapuu R., Kilk K., Mikelsaar M. (2015). Impact of probiotic L. plantarum TENSIA in different dairy products on anthropometric and blood biochemical indices of healthy adults. Benef Microbes 6(3):233-43
Pretto D., Vallas M., Pärna E., Tänavots A., Kiiman H., Kaart T. (2014). Short communication: Genetic correlation and heritability of milk coagulation traits within and across lactations in Holstein cows using multiple-lactation random regression animal models. J Dairy Sci 97:1–5 (http://dx.doi.org/ 10.3168/jds.2014-8270).
Rätsep M., Naaber P., Kõljalg S., Smidt I., Shkut E., Sepp E. (2014). Effect of Lactobacillus plantarum strains on clinical isolates of Clostridium difficile in vitro. Journal of Probiotic and Health. 2:1
Sharafedtinov K., Plotnikova O., Alexeeva R., Sentsova., T., Songisepp E., Stsepetova J., Smidt., I., Mikelsaar., M. (2013). Hypocaloric diet supplemented with probiotic cheese improves body mass index and blood pressure indices of obese hypertensive patients - a randomized double-blind placebo-controlled pilot study. Nutrition Journal., 12., 138 - 159.
Kullisaar T., Türk S., Punab M., Veskioja A.., Songisepp E., Zilmer K., Zilmer M. (2013). Dietary Modification of Lower Urinary Tract Symptoms with Fermented Whey Product. Open J Urol, 3: 114-120
Raudsepp P., Anton D., Roasto M., Meremäe K., Pedastsaar P., Mäesaar M., Raal A., Laikoja, K., Püssa, T. (2013). The antioxidative and antimicrobial properties of the blue honeysuckle (Lonicera caerulea L.), Siberian rhubarb (Rheum rhaponticum L.) and some other plants, compared to ascorbic acid and sodium nitrite. Food Control, 31:129 – 135.
Harzia H., Kilk K., Ariko T., Kass M., Soomets U., Jõudu I., Kaart T., Arney D., Kärt O., Ots M. (2013) Glycerol as glycogenic precursor in feed., effects on milk coagulation properties and metabolic profiles. J Dairy Res, 80 (2): 190-196.
Kass M., Ariko T., Samarütel J., Ling K., Jaakson H., Kaart T., Arney D., Kärt O., Ots M. (2013). Long-term oral drenching of crude glycerol to primiparous dairy cows in early lactation. Animal Feed Science and Technology. 184(1-4); 58 - 66.
Harzia H., IlvesA., Ots M., Henno M., Jõudu I., Kaart T., Ling K., Kärt O., Kilk K., Soomets U (2013). Alterations in milk metabolome and coagulation ability during the lactation of dairy cows. J Dairy Sci, 96(10): 6440 - 6448.
Songisepp E., Hütt P., Rätsep M., Shkut E., Kõljalg S., Truusalu K., Stsepetova J., Smidt I., Kolk H., Zagura M., Mikelsaar. M. (2012). Safety of probiotic cheese containing Lactobacillus plantarum Tensia according to a variety of health indices in different age groups. J Dairy Sci., 95(10):5495 - 5509.
Pretto D., Kaart T., Vallas M., Jõudu I., Henno M., Ancilotto L., Cassandro M., Pärna E. (2011). Relationships between milk coagulation property traits analyzed with different methodologies. JDairy Sci. 94(9):4336 – 4346
Štšepetova J., Sepp E., Kolk H., Lõivukene K., Songisepp E., Mikelsaar M. (2011). Diversity and metabolic impact of intestinal Lactobacillus sp. in healthy adults and the elderly. British J Nutr., 105(8):1235-44
Vallas M., Bovenhuis H., Kaart T., Pärna K., Kiiman H., Pärna E. (2010). Genetic parameters for milk coagulation properties in Estonian Holstein cows. J Dairy Sci., 93:3789 - 3796.
Meremäe K., Roasto M., Tamme T., Ivanova M., Hänninen M -L., Elias P . (2010). In vitro study of the antimicrobial effect of selected probiotics combined with prebiotics on Campylobacter jejuni. – Archiv für Lebensmittelhygiene., 61(4)., 132 – 138.
Meremäe K., Elias Priit., Tamme., Terje., Kramarenko., Toomas., Lillenberg., Merike., Karus., Avo., Hänninen M –L., Roasto M. (2010). The occurrence of Campylobacter spp. in Estonian broiler chicken production in 2002 - 2007. – Food Control., 21(3): 272 – 275.
Kaldmäe H., Olt A., Ots M., Kärt O. (2010). Erinevate kindlustuslisandite mõju lutsernisilo kvaliteedile. – Agraarteadus., XXI(1-2): 8 – 13.
Kaldmäe H., Leming R., Kass M., Lember A., Tölp S., Kärt O. (2010). Chemical composition and nutritional value of heat-treated and cold-pressed rapeseed cake. – Veterinarija ir Zootechnika., 49(71): 55 – 60.
Kaldmäe H., Olt A., Ots M., Kärt O.(2010). Erinevate kindlustuslisandite mõju lutsernisilo kvaliteedile. – Agraarteadus., XXI., nr 1-2., 8 – 13.
Mikelsaar M., Stsepetova J., Hütt P., Kolk H., Sepp E., Lõivukene K., Zilmer K., Zilmer M. (2010). Intestinal Lactobacillus sp. is associated with some cellular and metabolic characteristics of blood in elderly people . Anaerobe , 16(3): 240 - 246.
Truusalu K., Kullisaar T., Hütt P., Mahlapuu R., Aunapuu M., Arend A., Zilmer M., Mikelsaar R., Mikelsaar M. (2010). Immunological., antioxidative., and morphological response in combined treatment of ofloxacin and Lactobacillus fermentum ME-3 probiotic in Salmonella Typhimurium murine model. APMIS., Nov., 118 (11):864 - 72.
Kullisaar T., Songisepp E., Aunapuu M., Kilk K., Arend A., Mikelsaar M., Rehema A., Zilmer M. (2010). Complete Glutathione System in Probiotic L. fermentum ME-3. Applied Biochemistry and Microbiology., 46(5)., 481 - 486.
Kaldmäe H., Kärt O., Olt A., Selge A., Keres. I. (2009). Inonculant effects on red clover silage: fermentation products and nutritive value. – Agronomy Res., 7( 2): 793 –800.
Kaasik A., Ots M., Leming R. (2009). Relationship between the content of rumen degradable protein in dairy cow diets and emission of excreted ammonia nitrogen. – Veterinarija ir Zootechnika., 47(69):16 – 22.
Jõudu I., Henno M., Värv S., Viinalass., H., Püssa T., Kaart T., Kärt O. (2009). Ülevaade Eesti veiste piima laapumisomadustest ja seda mõjutavatest teguritest. – Agraarteadus., XX(1): 3 – 14.
Jõudu I., Henno M., Värv S., Viinalass H., Püssa T., Kaart T., Arney D., Kärt O. (2009). The effect of milk proteins on milk coagulation properties in Estonian dairy breeds. – Veterinary Medicine and Zootechnics. 46(68): 14 – 19.
Jõudu I., Henno M., Kaart T., Püssa T., Kärt O. (2008). The effect of milk proteins contents on the rennet coagulation properties of milk from individual dairy cows. – Int Dairy J., 18:964 - 967.
Henno M., Ots M, Jõudu I., Kaart T., Kärt O. (2008). Factors affecting the freezing point stability of milk from individual cows. – Int Dairy J 18:210 – 215
Huhtanen P., Seppälä A., Ots M., Ahvenjarvi S., Rinne M. (2008). In vitro gas production profiles to estimate extent and effective firstorder rate of NDF digestion in the rumen. – Journal of Animal Science., 86(3)., 651 – 659.
Pärna E., Kiiman H., Vallas M., Viinalass H., Saveli O., Pärna K. (2007). Development of a breeding objective for Estonian Holstein cattle. Agricultural and Food Science., Vol. 16., No. 3., pp. 212-221.
Pärna E., Kiiman H., Vallas M., Viinalass H., Saveli O., Pärna K. (2007). Development of a breeding objective for Estonian Holstein cattle. Agricultural and Food Science., Vol. 16., No. 3., pp. 212-221.
Jaakson H., Ling K., Kaldmäe H., Samarütel J., Kaart T., Kärt O. (2007). Influence of pre-partum feeding on periparturient metabolic status in Estonian Holstein cows. Veterinarija ir Zootechnika., 40(62):14-21.
3Stsepetova J., Sepp E., Julge K., Vaughan E., Mikelsaar M., Willem de Vos. (2007). Molecularly assessed shifts of Bifidobacterium ssp. and less diverse microbial communities are characteristic of 5-year-old allergic children. FEMS Immunol. Med. Microbiol 51: 260-269.
Kõll P., Mändar R., Marcotte H., Leibur H., Mikelsaar M., Hammarström L. (2007). Characterization of oral lactobacilli as potential probiotics for oral health. Oral Microbiol. Immunol. 22: 1-9.
Hütt P., Shchepetova J., Lõivukene K., Kullisaar T., Mikelsaar M. (2007). Antagonistic activity of probiotic lactobacilli and bifidobacteria against entero- and uropathogens. J. Appl. Microbiology., 100:1324-1332.
Jaakson H., Ling K., Kaldmäe H., Samarütel J., Kaart T., Kärt O. (2007). Influence of pre-partum feeding on post-partum intake., production and energy balance in Estonian Holstein cows. Veterinarija ir Zootechnika., 40(62):22-28.
Mihhejev K., Henno M., Ots M., Rihma E., Elias P., Kuusik S., Kärt O. (2007). Effects of fat-rich oil cakes on cheese fatty acid composition., and on cheese quality. – Veterinarija ir Zootechnika., 40(62):55 – 61.
Ling K., Waldmann A., Samarütel J., Jaakson H., Kaart T., Leesmäe A. (2007). Field trial on the relation of blood metabolites and body condition score to the recurrence of luteal activity in Estonian Holstein cows. Journal of Veterinary Medicine Series a-Physiology Pathology Clinical Medicine., 54(7):337 - 341.
Juhkam K., Elias P., Roasto M., Tamme T. (2007). Viability of Lactobacillus acidophilus in yoghurt containing inulin or oligofructose during refrigerated storage. – Milchwissenschaft., 62(1):52 – 54.
Kaldmäe H., Olt A., Ots M.., Kärt O., Songisepp E. (2007). Bioloogilise lisandi mõju punase ristiku-timuti silo fermentatsioonile ja toiteväärtusele.– Agraarteadus., XVIII(1)., 3 – 14.
Jõudu I., Henno M., Värv S., Kaart T., Kärt O.., Kalamees K. (2007). Milk protein genotypes and milk coagulation properties of Estonian Native cattle. – Agricultural and Food Science., 16.:222 – 231.
Rinne M., Olt A., Nousiainen J., Seppälä A., Tuori M., Paul C., Fraser M.D., Huhtanen., P. (2006). Prediction of legume silage digestibility from various laboratory methods. Grass and Forage Science 61: 354-362.
Kübarsepp I., Henno M., Viinalass H., Sabre D. (2005). Effect of k-casein and β- lactoglobulin genotypes on the milk rennet coagulation properties. Agronomy Research., 3(1):55 - 64.
Songisepp E., Kals J., Kullisaar T., Hütt P., Mändar R., Zilmer M., Mikelsaar M. (2005). Evaluation of the functional efficacy of a probiotic in healthy volunteers. Nutr J , 4:22.
Kübarsepp I., Henno M., Kärt O., Tupasela T. (2005). A comparison of the methods for determination of the rennet coagulation properties of milk. Acta Agriculturae Scandinavica., Section A - Animal Science., 55(4): 145